The persistent pool of HIV-1-infected cells is formed episodically during untreated infection

ABSTRACT Previous studies have shown that the majority of long-lived cells harboring persistent HIV-1 proviral genomes originates from viruses circulating in the year prior to antiretroviral therapy (ART) initiation, but a smaller proportion originates from viruses circulating much earlier in untrea...

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Bibliographic Details
Main Authors: Olivia D. Council, Lynn Tyers, Matthew Moeser, Amy Sondgeroth, Ean Spielvogel, Brian D. Richardson, Deelan Doolabh, Shuntai Zhou, Ann Emery, Nancie M. Archin, Bonnie Shook-Sa, David M. Margolis, Salim S. Abdool Karim, Sergei Kosakovsky Pond, Nigel Garrett, Melissa-Rose Abrahams, Sarah B. Joseph, Carolyn Williamson, Ronald Swanstrom
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2025-02-01
Series:Journal of Virology
Subjects:
HIV-1
reservoir
sequencing
Online Access:https://journals.asm.org/doi/10.1128/jvi.00979-24
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