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Translesion synthesis by AMV, HIV, and MMLVreverse transcriptases using RNA templates containing inosine, guanosine, and their 8-oxo-7,8-dihydropurine derivatives.

Inosine is ubiquitous and essential in many biological processes, including RNA-editing. In addition, oxidative stress on RNA has been a topic of increasing interest due, in part, to its potential role in the development/progression of disease. In this work we probed the ability of three reverse tra...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Madeline M Glennon, Austin Skinner, Mara Krutsinger, Marino J E Resendiz
التنسيق: Artigo
اللغة:Inglês
منشور في: Public Library of Science (PLoS) 2020-01-01
سلاسل:PLoS ONE
الوصول للمادة أونلاين:https://doi.org/10.1371/journal.pone.0235102
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