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Comparison of the TLR4/NFκB and NLRP3 signalling pathways in major organs of the mouse after intravenous injection of lipopolysaccharide

Context: Lipopolysaccharide (LPS) is often used to induce immunoinflammatory reactions. TLR4/NFκB and NLRP3 signalling are major factors for inflammation. Dexamethasone (DXM) has an anti-immunoinflammatory effect. Objective: To investigate the inflammatory reaction in pathological changes of organs...

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Principais autores: Qin Gong, Luling He, Mulan Wang, Shasha Zuo, Hongwei Gao, Yulin Feng, Lijun Du, Yingying Luo, Jun Li
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis Group 2019-01-01
Series:Pharmaceutical Biology
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Acceso en liña:http://dx.doi.org/10.1080/13880209.2019.1653326
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