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Pathogenesis of Autoimmune Male Infertility: Juxtacrine, Paracrine, and Endocrine Dysregulation

According to global data, there is a male reproductive potential decrease. Pathogenesis of male infertility is often associated with autoimmunity towards sperm antigens essential for fertilization. Antisperm autoantibodies (ASAs) have immobilizing and cytotoxic properties, impairing spermatogenesis,...

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Furkejuvvon:
Váldodahkkit: Valeriy A. Chereshnev, Svetlana V. Pichugova, Yakov B. Beikin, Margarita V. Chereshneva, Angelina I. Iukhta, Yuri I. Stroev, Leonid P. Churilov
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: MDPI AG 2021-10-01
Ráidu:Pathophysiology
Fáttát:
male infertility
varicocele
varicocelectomy
spermatozoa
sperm antigens
antisperm autoantibodies
Liŋkkat:https://www.mdpi.com/1873-149X/28/4/30
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