T cells suppress memory-dependent rapid mucous cell metaplasia in mouse airways

Abstract Background Airway epithelial cells (AECs) are crucial for mucosal and adaptive immunity but whether these cells respond in a memory-dependent manner is poorly studied. Previously, we have reported that LPS intratracheal instillation in rodents causes extensive neutrophilic inflammation and...

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Principais autores:	Hitendra S. Chand, Yohannes A. Mebratu, Marena Montera, Yohannes Tesfaigzi
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2016-10-01
Serija:	Respiratory Research
Teme:	Mucous cell metaplasia Epithelial memory LPS T cells Toll-like receptor 4 Epidermal growth factor receptor
Online dostop:	http://link.springer.com/article/10.1186/s12931-016-0446-0
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