Role of C-Terminal Phosphorylation of Lamin A in DNA Damage and Cellular Senescence

The nuclear matrix protein lamin A is a multifunctional protein with roles in DNA replication and repair, gene activation, transcriptional regulation, and maintenance of higher-order chromatin structure. Phosphorylation is the main determinant of lamin A mobility in the nucleus and nuclear membrane...

詳細記述

書誌詳細

主要な著者:	Ying Ao, Zhuping Wu, Zhiwei Liao, Juncong Lan, Jie Zhang, Pengfei Sun, Baohua Liu, Zimei Wang
フォーマット:	Artigo
言語:	Inglês
出版事項:	MDPI AG 2023-02-01
シリーズ:	Cells
主題:	lamin A phosphorylation DNA damage cellular senescence premature aging
オンライン･アクセス:	https://www.mdpi.com/2073-4409/12/4/639
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