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Dual and context-dependent role of the interleukin-33/soluble suppression of tumorigenicity 2 axis in obesity and adipose tissue inflammation

Abstract Background Obesity is increasingly recognized as a state of chronic, unresolved inflammation in which the interleukin (IL)-33/suppression of tumorigenicity 2 (ST2) axis may represent a key immunometabolic regulator. Objective We investigated circulating concentrations and adipose tissue exp...

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Principais autores: Marcos Casado, Javier Gómez-Ambrosi, Beatriz Ramírez, Sara Becerril, Amaia Rodríguez, Víctor Valentí, Rafael Moncada, Camilo Silva, Javier Escalada, Gema Frühbeck, Victoria Catalán
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2026-03-01
coleção:Molecular Medicine
Assuntos:
Obesity
Type 2 diabetes
Interleukin-33
sST2
Inflammation
Visceral adipose tissue
Acesso em linha:https://doi.org/10.1186/s10020-026-01454-z
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