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The essential elements for the noncovalent association of two DNA ends during NHEJ synapsis

During a process termed synapsis, the two DNA ends at a double-strand break (DSB) are brought together into physical proximity. Here, the authors use a single-molecule FRET approach with purified proteins to investigate the mechanism of synapsis in DSB repair by non-homologous DNA end joining (NHEJ)...

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Bibliografische gegevens
Hoofdauteurs: Bailin Zhao, Go Watanabe, Michael J. Morten, Dylan A. Reid, Eli Rothenberg, Michael R. Lieber
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Portfolio 2019-08-01
Reeks:Nature Communications
Online toegang:https://doi.org/10.1038/s41467-019-11507-z
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