Metabolomics analysis identifies intestinal microbiota-derived biomarkers of colonization resistance in clindamycin-treated mice.

BACKGROUND:The intestinal microbiota protect the host against enteric pathogens through a defense mechanism termed colonization resistance. Antibiotics excreted into the intestinal tract may disrupt colonization resistance and alter normal metabolic functions of the microbiota. We used a mouse model...

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主要な著者:	Robin L P Jump, Alex Polinkovsky, Kelly Hurless, Brett Sitzlar, Kevin Eckart, Myreen Tomas, Abhishek Deshpande, Michelle M Nerandzic, Curtis J Donskey
フォーマット:	Artigo
言語:	Inglês
出版事項:	Public Library of Science (PLoS) 2014-01-01
シリーズ:	PLoS ONE
オンライン･アクセス:	http://europepmc.org/articles/PMC4079339?pdf=render
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