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Plasma exosomal lncRNA-related signatures define molecular subtypes and predict survival and treatment response in hepatocellular carcinoma

BackgroundHepatocellular carcinoma (HCC) faces challenges in early diagnosis, prognosis, and treatment stratification due to molecular heterogeneity. This study aimed to establish a plasma exosomal long non-coding RNA (lncRNA)-based framework for molecular classification, prognostication, and therap...

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Principais autores: Fangmin Zhong, Fangyi Yao, Xin-Lu Wang, Zihao Wang, Bo Huang, Jing Liu, Xiaozhong Wang, Lei Zhang
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2025-10-01
Serier:Frontiers in Immunology
Fag:
hepatocellular carcinoma
exosomal lncRNA
molecular subtype
prognosis
treatment response
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1663943/full
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