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Novel point and combo-mutations in the genome of hepatitis B virus-genotype D: characterization and impact on liver disease progression to hepatocellular carcinoma.

BACKGROUND: The contribution of chronic hepatitis B virus (HBV) infection in the pathogenesis of hepatocellular carcinoma (HCC) through progressive stages of liver fibrosis is exacerbated by the acquisition of naturally occurring mutations in its genome. This study has investigated the prevalence of...

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Bibliografische Detailangaben
Hauptverfasser: Somenath Datta, Alip Ghosh, Debanjali Dasgupta, Amit Ghosh, Shrabasti Roychoudhury, Gaurav Roy, Soumyojit Das, Kausik Das, Subash Gupta, Keya Basu, Analabha Basu, Simanti Datta, Abhijit Chowdhury, Soma Banerjee
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2014-01-01
Schriftenreihe:PLoS ONE
Online-Zugang:http://europepmc.org/articles/PMC4198185?pdf=render
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