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Inhibition of Phosphatidylinositol 3-Kinase by Pictilisib Blocks Influenza Virus Propagation in Cells and in Lungs of Infected Mice

Influenza virus (IV) infections are considered to cause severe diseases of the respiratory tract. Beyond mild symptoms, the infection can lead to respiratory distress syndrome and multiple organ failure. Occurrence of resistant seasonal and pandemic strains against the currently licensed antiviral m...

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Bibliografiske detaljer
Principais autores: Stefanie Deinhardt-Emmer, Laura Jäckel, Clio Häring, Sarah Böttcher, Janine J. Wilden, Brigitte Glück, Regine Heller, Michaela Schmidtke, Mirijam Koch, Bettina Löffler, Stephan Ludwig, Christina Ehrhardt
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2021-05-01
Serier:Biomolecules
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Online adgang:https://www.mdpi.com/2218-273X/11/6/808
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