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Growth differentiation factor 15 alleviates diastolic dysfunction in mice with experimental diabetic cardiomyopathy

Summary: Growth differentiation factor 15 (GDF15) is a peptide with utility in obesity, as it decreases appetite and promotes weight loss. Because obesity increases the risk for type 2 diabetes (T2D) and cardiovascular disease, it is imperative to understand the cardiovascular actions of GDF15, espe...

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Principais autores: Jordan S.F. Chan, Seyed Amirhossein Tabatabaei Dakhili, Maria Areli Lorenzana-Carrillo, Keshav Gopal, Serena M. Pulente, Amanda A. Greenwell, Kunyan Yang, Christina T. Saed, Magnus J. Stenlund, Sally R. Ferrari, Indiresh A. Mangra-Bala, Tanin Shafaati, Rakesh K. Bhat, Farah Eaton, Michael Overduin, Sebastian Beck Jørgensen, Gregory R. Steinberg, Erin E. Mulvihill, Gopinath Sutendra, John R. Ussher
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2024-08-01
coleção:Cell Reports
Assuntos:
CP: Metabolism
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2211124724009021
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