Biological properties and in silico studies of thiazolopyrimidine derivatives active against visceral and cutaneous Leishmania spp. amastigote forms

Visceral leishmaniasis, the most severe form of the disease, is caused by L. donovani and L. infantum parasites; cutaneous leishmaniasis is the most common endemic form of leishmaniasis and mainly caused by L. tropica and L. major. We have previously described a series of thiazolopyrimidine derivati...

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Hlavní autoři:	Gulsah Bayraktar, Pascal Marchand, Euzébio Guimarães Barbosa, Marilia Cecilia da Silva, Karen Cacilda Weber, Sandrine Cojean, Merve Saylam, Huseyin Istanbullu
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2024-12-01
Edice:	European Journal of Medicinal Chemistry Reports
Témata:	Antileishmanial Axenic amastigote Intramacrophage amastigote Thiazolopyrimidine In silico studies
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2772417424001006
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