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A case of Alemtuzumab-induced neutropenia in multiple sclerosis in association with the expansion of large granular lymphocytes

Abstract Background Alemtuzumab has been demonstrated to reduce the risks of relapse and accumulation of sustained disability in Multiple Sclerosis (MS) patients compared to β-interferon. It acts against CD52, leading primarily to lymphopenia. Recent data have shown that mild neutropenia is observed...

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Автори: A. G. Vakrakou, D. Tzanetakos, S. Valsami, E. Grigoriou, K. Psarra, J. Tzartos, M. Anagnostouli, E. Andreadou, M. E. Evangelopoulos, G. Koutsis, C. Chrysovitsanou, E. Gialafos, A. Dimitrakopoulos, L. Stefanis, C. Kilidireas
Формат: Artigo
Мова:Inglês
Опубліковано: BMC 2018-10-01
Серія:BMC Neurology
Предмети:
Multiple sclerosis
Alemtuzumab
Neutropenia
Large granular cells
Онлайн доступ:http://link.springer.com/article/10.1186/s12883-018-1183-4
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