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Contribution of MLH1, MSH2, and MSH6 large genomic rearrangements to Pakistani colorectal cancer patients

Abstract Background Colorectal cancer (CRC) is the fourth most common cancer in Pakistan and poses significant public health challenges. While the majority of CRC cases are sporadic, ~ 5–10% are hereditary, linked to germline pathogenic variants (PVs) in mismatch repair genes (MLH1, MSH2, MSH6, PMS2...

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Váldodahkkit: Humaira Naeemi, Noor Muhammad, Asif Loya, Muhammed Aasim Yusuf, Muhammad Usman Rashid
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: BMC 2025-11-01
Ráidu:Hereditary Cancer in Clinical Practice
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Liŋkkat:https://doi.org/10.1186/s13053-025-00327-6
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