Recombinant Mammalian Prions: The “Correctly” Misfolded Prion Protein Conformers

Generating a prion with exogenously produced recombinant prion protein is widely accepted as the ultimate proof of the prion hypothesis. Over the years, a plethora of misfolded recPrP conformers have been generated, but despite their seeding capability, many of them have failed to elicit a fatal neu...

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Hlavní autoři:	Jiyan Ma, Jingjing Zhang, Runchuan Yan
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2022-08-01
Edice:	Viruses
Témata:	transmissible spongiform encephalopathies prion prion protein misfolding recombinant prion seeding
On-line přístup:	https://www.mdpi.com/1999-4915/14/9/1940
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