Synthesis and metabolism of leukotrienes in γ-glutamyl transpeptidase deficiency

Leukotrienes (LTs) are active lipid mediators derived in the 5-lipoxygenase pathway. LTC4, the primary cysteinyl LT, is cleaved by γ-glutamyl transpeptidase (GGT), resulting in LTD4. We studied the synthesis and metabolism of LTs in three patients with GGT deficiency. LTs were analyzed in urine, pla...

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מידע ביבליוגרפי

Principais autores:	Ertan Mayatepek, Jürgen G. Okun, Thomas Meissner, Birgit Assmann, Judith Hammond, Johannes Zschocke, Wolf-Dieter Lehmann
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Elsevier 2004-05-01
סדרה:	Journal of Lipid Research
נושאים:	cysteinyl leukotriene glutathione 5-lipoxygenase pathway
גישה מקוונת:	http://www.sciencedirect.com/science/article/pii/S0022227520318307
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