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Estimating colocalization probability from limited summary statistics

Abstract Background Colocalization is a statistical method used in genetics to determine whether the same variant is causal for multiple phenotypes, for example, complex traits and gene expression. It provides stronger mechanistic evidence than shared significance, which can be produced through sepa...

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Bibliografische Detailangaben
Hauptverfasser: Emily A. King, Fengjiao Dunbar, Justin Wade Davis, Jacob F. Degner
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2021-05-01
Schriftenreihe:BMC Bioinformatics
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Online-Zugang:https://doi.org/10.1186/s12859-021-04170-z
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