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Establishing the Thermodynamic Cards of Dipine Models’ Oxidative Metabolism on 21 Potential Elementary Steps

Dipines are a type of important antihypertensive drug as L-calcium channel blockers, whose core skeleton is the 1,4-dihydropyridine structure. Since the dihydropyridine ring is a key structural factor for biological activity, the thermodynamics of the aromatization dihydropyridine ring is a signific...

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Autori principali: Guang-Bin Shen, Shun-Hang Gao, Yan-Wei Jia, Xiao-Qing Zhu, Bao-Chen Qian
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2024-08-01
Serie:Molecules
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Accesso online:https://www.mdpi.com/1420-3049/29/15/3706
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