Synthesis of Novel Pyrido[4,3-e][1,2,4]triazino[3,2-c][1,2,4]thiadiazine 6,6-dioxide Derivatives with Potential Anticancer Activity

A series of novel 3-/2,3-substituted pyrido[4,3-e][1,2,4]triazino[3,2-c][1,2,4]thiadiazine 6,6-dioxides 4–28 have been synthesized by the reaction of 3-amino-2-(4-thioxo-1,4-dihydropyridin-3-yl-sulfonyl)guanidine with either 2-oxoalkanoic acids and its esters, or phenylglyoxylic hydrates in glacial...

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Principais autores:	Jarosław Sławiński, Aleksandra Grzonek, Beata Żołnowska, Anna Kawiak
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2015-12-01
coleção:	Molecules
Assuntos:	pyrido[4,3-e][1,2,4]triazino[3,2-c][1,2,4]thiadiazine 6,6-dioxides synthesis NMR studies cytotoxic activity
Acesso em linha:	http://www.mdpi.com/1420-3049/21/1/41
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