Mosaic cis-regulatory evolution drives transcriptional partitioning of HERVH endogenous retrovirus in the human embryo

The human endogenous retrovirus type-H (HERVH) family is expressed in the preimplantation embryo. A subset of these elements are specifically transcribed in pluripotent stem cells where they appear to exert regulatory activities promoting self-renewal and pluripotency. How HERVH elements achieve suc...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Thomas A Carter, Manvendra Singh, Gabrijela Dumbović, Jason D Chobirko, John L Rinn, Cédric Feschotte
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	eLife Sciences Publications Ltd 2022-02-01
Serie:	eLife
Soggetti:	endogenous retroviruses genomics primate evolution embryonic stem cells HERVH transposable elements
Accesso online:	https://elifesciences.org/articles/76257
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!