Molecular basis of ParA ATPase activation by the CTPase ParB during bacterial chromosome segregation

Abstract DNA segregation by bacterial ParABS systems is mediated by transient tethering interactions between nucleoid-bound dimers of the ATPase ParA and centromere (parS)-associated complexes of the clamp-forming CTPase ParB. The lifetime of these interactions is limited by the ParB-dependent activ...

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Autors principals:	Lucas Schnabel, Manuel Osorio-Valeriano, Cecilia Perez-Borrajero, Wieland Steinchen, Christopher-Nils Mais, Bernd Simon, Juri Hanßmann, Maria Thamm, Janosch Hennig, Gert Bange, Martin Thanbichler
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2025-09-01
Col·lecció:	Nature Communications
Accés en línia:	https://doi.org/10.1038/s41467-025-63976-0
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