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New pairings and deorphanization among the atypical chemokine receptor family — physiological and clinical relevance

Atypical chemokine receptors (ACKRs) form a small subfamily of receptors (ACKR1–4) unable to trigger G protein-dependent signaling in response to their ligands. They do, however, play a crucial regulatory role in chemokine biology by capturing, scavenging or transporting chemokines, thereby regulati...

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Библиографические подробности
Главные авторы: Martyna Szpakowska, Giulia D’Uonnolo, Rafael Luís, Ana Alonso Bartolomé, Marcus Thelen, Daniel F. Legler, Andy Chevigné
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2023-04-01
Серии:Frontiers in Immunology
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Online-ссылка:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1133394/full
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