CD8+ T cell exhaustion driven by metabolic reprogramming
Abstract CD8⁺ T cells are central to adaptive immunity, with their function tightly linked to cellular metabolism. Naïve T cells rely on oxidative phosphorylation, effector T cells shift to aerobic glycolysis for rapid proliferation, and memory T cells depend on fatty acid oxidation and efficient mi...
Guardado en:
| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BMC
2026-04-01
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| Colección: | Cancer Cell International |
| Materias: | |
| Acceso en línea: | https://doi.org/10.1186/s12935-026-04287-2 |
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