Effect of polypharmacy on plasma bepridil concentration in patients with heart failure: a multicenter retrospective study

Abstract Background Polypharmacy, defined as the concurrent use of over six drugs, is common in the treatment of heart failure (HF); however, unpredictable drug interactions with bepridil may occur. In this study, we have elucidated the influence of polypharmacy on plasma bepridil concentrations in...

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Autores principales:	Yuki Asai, Hiroki Arihara, Saki Omote, Ena Tanio, Saena Yamashita, Takashi Higuchi, Ei Hashimoto, Momoko Yamada, Hinako Tsuji, Yoshihiro Kondo, Makoto Hayashi, Yoshiaki Yamamoto
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2023-03-01
Colección:	Journal of Pharmaceutical Health Care and Sciences
Materias:	Bepridil Heart failure Polypharmacy Drug-drug interaction Therapeutic drug monitoring
Acceso en línea:	https://doi.org/10.1186/s40780-023-00278-x
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