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Anti-tumor targeted drug delivery systems mediated by aminopeptidase N/CD13

Aminopeptidase N (APN)/CD13 is a transmembrane glycoprotein, which is overexpressed on tumor neovascular endothelial cells and most tumor cells, where it plays an important role in tumor angiogenesis. Peptides containing the Asn-Gly-Arg (NGR) motif can specifically recognize APN/CD13 allowing them t...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Xun Wang, Bin Wang, Qiang Zhang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2011-08-01
Schriftenreihe:Acta Pharmaceutica Sinica B
Schlagworte:
Online-Zugang:http://www.sciencedirect.com/science/article/pii/S2211383511000402
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