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Flip/flop mating-type switching in the methylotrophic yeast Ogataea polymorpha is regulated by an Efg1-Rme1-Ste12 pathway.

In haploid cells of Ogataea (Hansenula) polymorpha an environmental signal, nitrogen starvation, induces a reversible change in the structure of a chromosome. This process, mating-type switching, inverts a 19-kb DNA region to place either MATa or MATα genes under centromeric repression of transcript...

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Autori principali: Sara J Hanson, Kevin P Byrne, Kenneth H Wolfe
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2017-11-01
Serie:PLoS Genetics
Accesso online:http://europepmc.org/articles/PMC5720833?pdf=render
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