Human umbilical cord-derived mesenchymal stem cells alleviate insulin resistance in diet-induced obese mice via an interaction with splenocytes

Abstract Background Previous research has demonstrated that the spleen plays an important role in mesenchymal stem cell (MSC)-mediated alleviation of acute inflammation, as MSC infusion increases the spleen-derived anti-inflammatory cytokine interleukin 10 (IL-10) levels. However, studies on splenic...

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Autors principals:	Jing Xue, Jieqing Gao, Yulin Gu, Aihong Wang, Songyan Yu, Bing Li, Yaqi Yin, Jie Wang, Wanlu Su, Haixia Zhang, Weizheng Ren, Weijun Gu, Zhaohui Lv, Yiming Mu, Yu Cheng
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2022-03-01
Col·lecció:	Stem Cell Research & Therapy
Matèries:	Insulin resistance Obesity Spleen Mesenchymal stem cells Macrophage Regulatory T cell
Accés en línia:	https://doi.org/10.1186/s13287-022-02791-6
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