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Aromatic-Turmerone Analogs Protect Dopaminergic Neurons in Midbrain Slice Cultures through Their Neuroprotective Activities

Parkinson’s disease (PD) is a neurodegenerative disorder characterized by the loss of dopaminergic neurons in the substantia nigra. The inflammatory activation of microglia participates in dopaminergic neurodegeneration in PD. Therefore, chemicals that inhibit microglial activation are considered to...

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Principais autores: Yuria Hori, Reiho Tsutsumi, Kento Nasu, Alex Boateng, Yasuhiko Ashikari, Masaharu Sugiura, Makoto Nakajima, Yuki Kurauchi, Akinori Hisatsune, Hiroshi Katsuki, Takahiro Seki
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2021-05-01
Serier:Cells
Fag:
aromatic-turmerone
dopaminergic neurons
microglia
Nrf2
Online adgang:https://www.mdpi.com/2073-4409/10/5/1090
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