Molecular crowding inhibits U-insertion/deletion RNA editing in vitro: consequences for the in vivo reaction.
Mitochondrial pre-mRNAs in African trypanosomes are edited to generate functional transcripts. The reaction is typified by the insertion and deletion of U nucleotides and is catalyzed by a macromolecular complex, the editosome. Editosomes bind pre-edited mRNA/gRNA pairs and the reaction can be recap...
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| Principais autores: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science (PLoS)
2013-01-01
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| Serija: | PLoS ONE |
| Online dostop: | http://europepmc.org/articles/PMC3871654?pdf=render |
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