Dendritic Cells Generated From Mops condylurus, a Likely Filovirus Reservoir Host, Are Susceptible to and Activated by Zaire Ebolavirus Infection

Ebola virus infection of human dendritic cells (DCs) induces atypical adaptive immune responses and thereby exacerbates Ebola virus disease (EVD). Human DCs, infected with Ebola virus aberrantly express low levels of the DC activation markers CD80, CD86, and MHC class II. The T cell responses ensuin...

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Principais autores:	Kathryn M. Edenborough, Marcel Bokelmann, Angelika Lander, Emmanuel Couacy-Hymann, Johanna Lechner, Oliver Drechsel, Bernhard Y. Renard, Aleksandar Radonić, Heinz Feldmann, Andreas Kurth, Joseph Prescott
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2019-10-01
Series:	Frontiers in Immunology
Assuntos:	Ebola virus (EBOV) reservoir hosts dendritic cells transcriptome Mops condylurus filovirus
Acceso en liña:	https://www.frontiersin.org/article/10.3389/fimmu.2019.02414/full
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