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High level of oxidized nucleosides in thyroid mitochondrial DNA; damaging effects of Fenton reaction substrates

<p>Abstract</p> <p>Background</p> <p>The mitochondrial DNA (mtDNA) lies in close proximity to the free radical-producing electron transport chain, thus, it is highly prone to oxidative damage. Oxyphilic type of follicular thyroid carcinoma consists of cells filled – almost exclusively – with aberran...

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Autori principali: Karbownik-Lewińska Małgorzata, Stępniak Jan, Lewiński Andrzej
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2012-12-01
Serie:Thyroid Research
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Accesso online:http://www.thyroidresearchjournal.com/content/5/1/24
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