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Development and Characterization of Paclitaxel-loaded PLGA Nanoparticles and Evaluation of Cytotoxicity on MCF-7 Cell Line by MTT Assay

Paclitaxel (PTX), cytotoxic agent extracted from Taxus brevifolia has significant antineoplastic activity against breast cancer. Poly d,l-lactide-co-glycolide (PLGA) has been widely used for the preparation of nanoparticles carrying cytotoxic drug agents. The aim of this study was to evaluate the ef...

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Principais autores: Merve Çelik Tekeli, Çiğdem Yücel, Sedat Ünal, Gökçe Şeker Karatoprak, Yeşim Aktaş, Erem Bilensoy
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2017-11-01
coleção:Proceedings
Assuntos:
PLGA
nanoparticle
MCF-7
MTT
Cytotoxicity
Acesso em linha:https://www.mdpi.com/2504-3900/1/10/1030
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