Small molecule conjugates with selective estrogen receptor β agonism promote anti-aging benefits in metabolism and skin recovery

Estrogen is imperative to mammalian reproductivity, metabolism, and aging. However, the hormone activating estrogen receptor (ERs) α can cause major safety concerns due to the enrichment of ERα in female tissues and certain malignancies. In contrast, ERβ is more broadly expressed in metabolic tissue...

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Detalhes bibliográficos

Principais autores:	Tarik Zahr, Vijay K. Boda, Jian Ge, Lexiang Yu, Zhongzhi Wu, Jianwen Que, Wei Li, Li Qiang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-05-01
coleção:	Acta Pharmaceutica Sinica B
Assuntos:	Estrogen receptor β Aging Metabolism Skin injury Muscle metabolism Small molecule conjugates
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2211383524000170
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