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KoMethylNet: a novel epigenetic clock based on neural network analysis of DNA methylation data and epigenetic age acceleration in a Korean population

Abstract Background Epigenetic clocks have been extensively investigated in individuals of European ancestry and may be suboptimal in East Asians. We developed a novel epigenetic clock (KoMethylNet) using neural network analysis of DNA methylation (DNAm) data from the Korean population to predict ch...

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Principais autores: Dabin Yun, Kwangyeon Oh, Yujin Kim, Yong Min Ahn, Hemang M. Parikh, Xiaoxi Meng, Zhaoming Wang, Nan Song
格式: Artigo
语言:Inglês
出版: BMC 2025-12-01
丛编:BMC Medicine
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在线阅读:https://doi.org/10.1186/s12916-025-04564-3
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