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METTL14 modulates the progression and ferroptosis of colitis by regulating the stability of m6A-modified GPX4

Abstract Ulcerative colitis (UC) is non-specific inflammatory bowel disease. UC development and progression were closely associated with epigenetic modifications. Nevertheless, the specific relationship between N6-methyladenosine (m6A) modification at RNA transcription levels and UC pathogenesis rem...

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Autori principali: Yuhua Chen, Weicong Fan, Ying Lyu, Jingsheng Liao, Ying Zhou
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2025-02-01
Serie:European Journal of Medical Research
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Accesso online:https://doi.org/10.1186/s40001-025-02334-8
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