Impaired Secondary Platelet Response in Chronic Kidney Disease as a Consequence of Prior Platelet Activation

Summary: Patients with chronic kidney disease (CKD) are at increased risk of thrombotic and hemorrhagic complications. Findings on platelet defects in CKD are conflicting. Therefore, we examined platelet function in CKD stage 3 to 5 dialysis patients without antithrombotic therapy, in CKD5D/hemodial...

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Principais autores:	Constance C.F.M.J. Baaten, PhD, Julia Wollenhaupt, PhD, Tobias M. Henning, MD, Sonja Vondenhoff, MS, Jonas R. Schröer, MD, Eleni Stamellou, MD, PhD, MS, Turgay Saritas, MD, PhD, Berkan Kurt, MD, Leonard Boger, MD, Alessandra Antwerpen, Juliane Hermann, PhD, Magdolna Nagy, PhD, Marieke Sternkopf, PhD, Eva Miriam Buhl, PhD, Ute Raffetseder, PhD, Paola E.J. van der Meijden, PhD, Marijke J.E. Kuijpers, PhD, Henri M.H. Spronk, PhD, Stefan J. Schunk, MD, Joachim Jankowski, PhD, Danilo Fliser, MD, Thimoteus Speer, MD, PhD, Peter Boor, MD, PhD, Rafael Kramann, MD, PhD, Florian Kahles, MD, Jürgen Floege, MD, Nikolaus Marx, MD, Heidi Noels, PhD
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2025-09-01
coleção:	JACC: Basic to Translational Science
Assuntos:	acetylsalicylic acid bleeding chronic kidney disease platelets thrombosis
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2452302X25003080
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