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Hypomethylation of the miRNA-34a gene promoter is associated with Severe Preeclampsia

Purpose: PE is a pregnancy-specific complication, which genetic and epigenetic factors play key roles in its pathogenesis. DNA methylation is a main epigenetic alteration with important roles in gene regulation. Micro RNAs (miRNAs) as another member of epigenetic machinery regulate the gene expressi...

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Autors principals: Mahnaz Rezaei, Fatemeh Eskandari, Abbas Mohammadpour-Gharehbagh, Mahdiyeh Harati-Sadegh, Batool Teimoori, Saeedeh Salimi
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis Group 2019-02-01
Col·lecció:Clinical and Experimental Hypertension
Accés en línia:http://dx.doi.org/10.1080/10641963.2018.1451534
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