Downregulation of ubiquitous microRNA-320 in hepatocytes triggers RFX1-mediated FGF1 suppression to accelerate MASH progression

Metabolic dysfunction-associated steatohepatitis (MASH), a severe type of metabolic dysfunction-associated steatotic liver disease (MASLD), is a leading etiology of end-stage liver disease worldwide, posing significant health and economic burdens. microRNA-320 (miR-320), a ubiquitously expressed and...

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Autores principales:	Liu Yang, Wenjun Li, Yingfen Chen, Ru Ya, Shengying Qian, Li Liu, Yawen Hao, Qiuhong Zai, Peng Xiao, Seonghwan Hwang, Yong He
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Elsevier 2025-08-01
Colección:	Acta Pharmaceutica Sinica B
Materias:	miR-320 MASLD RFX1 FGF1 AMPK
Acceso en línea:	http://www.sciencedirect.com/science/article/pii/S2211383525004101
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