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In Well‐Treated Celiac Patients Low‐Level Mucosal Inflammation Predicts Response to 14‐day Gluten Challenge

Abstract In celiac disease (CeD), gluten activates adaptive immune cells that cause damage to the small intestinal mucosa. Histological evaluation of intestinal biopsies allows for grading of disease severity. CeD can effectively be treated with a life‐long gluten‐free diet. Gluten challenge of trea...

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Autori principali: Jorunn Stamnaes, Daniel Stray, Maria Stensland, Vikas K. Sarna, Tuula A. Nyman, Knut E. A. Lundin, Ludvig M. Sollid
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wiley 2021-02-01
Serie:Advanced Science
Soggetti:
celiac disease
gluten challenge
laser capture microdissection
mass spectrometry
tissue proteomics
Accesso online:https://doi.org/10.1002/advs.202003526
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