Development and validation of an interpretable prediction model using spatial patterns of tumor-infiltrating lymphocytes in H&E-stained whole-slide images for immune subtyping of lung adenocarcinoma

ObjectiveTo develop an interpretable prediction model for lung adenocarcinoma immune subtyping by quantifying spatial distribution patterns of tumor-infiltrating lymphocytes in H&E whole-slide images, providing a computational tool for tumor immune microenvironment evaluation.MethodsImmune subty...

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Váldodahkkit:	Xia Li, Hai-Zhen Qin, Jing-Yu Wei, Kang-Lai Wei, Zhao-Quan Huang
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Frontiers Media S.A. 2026-05-01
Ráidu:	Frontiers in Immunology
Fáttát:	computational pathology immune subtyping interpretable model lung adenocarcinoma tumor-infiltrating lymphocytes
Liŋkkat:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1773927/full
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