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Platelets Aggregate With Neutrophils and Promote Skin Pathology in Psoriasis

Psoriasis is a frequent systemic inflammatory autoimmune disease characterized primarily by skin lesions with massive infiltration of leukocytes, but frequently also presents with cardiovascular comorbidities. Especially polymorphonuclear neutrophils (PMNs) abundantly infiltrate psoriatic skin but t...

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Principais autores: Franziska Herster, Zsofia Bittner, Marius Cosmin Codrea, Nathan K. Archer, Martin Heister, Markus W. Löffler, Simon Heumos, Joanna Wegner, Ramona Businger, Michael Schindler, David Stegner, Knut Schäkel, Stephan Grabbe, Kamran Ghoreschi, Lloyd S. Miller, Alexander N. R. Weber
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019-08-01
coleção:Frontiers in Immunology
Assuntos:
psoriasis
neutrophil
platelet
platelet-neutrophil complexes (PNCs)
imiquimod
Acesso em linha:https://www.frontiersin.org/article/10.3389/fimmu.2019.01867/full
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