Hsf1 and the molecular chaperone Hsp90 support a ‘rewiring stress response’ leading to an adaptive cell size increase in chronic stress

Cells are exposed to a wide variety of internal and external stresses. Although many studies have focused on cellular responses to acute and severe stresses, little is known about how cellular systems adapt to sublethal chronic stresses. Using mammalian cells in culture, we discovered that they adap...

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Principais autores:	Samarpan Maiti, Kaushik Bhattacharya, Diana Wider, Dina Hany, Olesya Panasenko, Lilia Bernasconi, Nicolas Hulo, Didier Picard
Format:	Artigo
Jezik:	Inglês
Izdano:	eLife Sciences Publications Ltd 2023-12-01
Serija:	eLife
Teme:	proteostasis translation aging cytoplasmic density stress adaptation senescence
Online dostop:	https://elifesciences.org/articles/88658
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