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Deletion of the Human Cytomegalovirus US2 to US11 Gene Family Members Impairs the Type-I Interferon Response

Infection of cells with the human cytomegalovirus (HCMV) triggers the expression of interferon-stimulated genes (ISGs). ISGs encode proteins with antiviral functions, such as inhibiting viral replication, promoting cell death of infected cells and enhancing immune responses. HCMV has evolved mechani...

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Principais autores: Inessa Penner, Nadine Krämer, Julia Hirsch, Nicole Büscher, Hanno Schmidt, Bodo Plachter
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI AG 2025-03-01
סדרה:Viruses
נושאים:
cytomegalovirus
immune evasion
interferon
interferon stimulated genes
גישה מקוונת:https://www.mdpi.com/1999-4915/17/3/426
תגים: הוספת תג
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