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Medullary cavity expansion is mediated by distinct cell populations during fetal bone development

Abstract Bone marrow (BM) is the primary site of postnatal hematopoiesis, yet how it is established during embryogenesis remains poorly understood. BM formation is initiated by the invasion of vascular and mesenchymal cells into a preformed cartilage template, generating the primary ossification cen...

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Bibliografische gegevens
Hoofdauteurs: Eriko Sumiya, Kohei Saeki, Kenta Nakano, Chie Kikutake, Noriko Kurisaki, Natsuko Nakaima, Mami Kurumata-Shigeto, Yumiko Kitada, Yuka Morioka, Yasuhiro Go, Mikita Suyama, Yuki Yoshimura, Motohito Goto, Mamoru Ito, Manabu Nakayama, Haruhiko Akiyama, Lucie Peduto, Tadashi Okamura, Yuki Matsushita, Shinichiro Sawa
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Portfolio 2026-04-01
Reeks:Nature Communications
Online toegang:https://doi.org/10.1038/s41467-026-71952-5
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