Circular RNA circPHLPP2 promotes tumor growth and anti-PD-1 resistance through binding ILF3 to regulate IL36γ transcription in colorectal cancer

Abstract Background Most Colorectal Cancer (CRC) patients exhibit limited responsiveness to anti-programmed cell death protein 1 (PD-1) therapy, with the underlying mechanisms remaining elusive. Circular RNAs (circRNAs) play a significant role in tumorigenesis and development, with potential applica...

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Bibliografische gegevens

Hoofdauteurs:	Yan Hu, Ze-Rong Cai, Ren-Ze Huang, De-Shen Wang, Huai-Qiang Ju, Dong-Liang Chen
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	BMC 2024-12-01
Reeks:	Molecular Cancer
Onderwerpen:	CircPHLPP2 Colorectal cancer NK cell Immune evasion
Online toegang:	https://doi.org/10.1186/s12943-024-02192-8
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