Neutralizing Activity of Anti-interferon-γ Autoantibodies in Adult-Onset Immunodeficiency Is Associated With Their Binding Domains

Adult-onset immunodeficiency (AOID) with anti-interferon-γ (IFN-γ) autoantibodies (autoAbs) is an emerging immunodeficiency syndrome in Asian countries. The presence of neutralizing anti-IFN-γ autoAbs are significantly associated with severe disseminated opportunistic infections. However, the charac...

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Principais autores:	Umpa Yasamut, Weeraya Thongkum, Sutpirat Moonmuang, Supachai Sakkhachornphop, Romanee Chaiwarith, Jutarat Praparattanapan, Jiraprapa Wipasa, Kriangkrai Chawansuntati, Khuanchai Supparatpinyo, Ethan Lai, Chatchai Tayapiwatana
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2019-08-01
Serija:	Frontiers in Immunology
Teme:	interferon-γ anti-interferon-γ autoantibody neutralizing antibody competitive-binding ELISA adult-onset immunodeficiency
Online dostop:	https://www.frontiersin.org/article/10.3389/fimmu.2019.01905/full
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