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Mitigation of total body irradiation-induced mortality and hematopoietic injury of mice by a thrombopoietin mimetic (JNJ-26366821)

Abstract The threat of a nuclear attack has increased in recent years highlighting the benefit of developing additional therapies for the treatment of victims suffering from Acute Radiation Syndrome (ARS). In this work, we evaluated the impact of a PEGylated thrombopoietin mimetic peptide, JNJ-26366...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Vidya P. Kumar, Gregory P. Holmes-Hampton, Shukla Biswas, Sasha Stone, Neel Kamal Sharma, Bernadette Hritzo, Mary Guilfoyle, Gary Eichenbaum, Chandan Guha, Sanchita P. Ghosh
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2022-03-01
Schriftenreihe:Scientific Reports
Online-Zugang:https://doi.org/10.1038/s41598-022-07426-7
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