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Renoprotective and haemodynamic effects of adiponectin and peroxisome proliferator-activated receptor agonist, pioglitazone, in renal vasculature of diabetic Spontaneously hypertensive rats.

Pioglitazone, a therapeutic drug for diabetes, possesses full PPAR-γ agonist activity and increase circulating adiponectin plasma concentration. Plasma adiponectin concentration decreases in hypertensive patients with renal dysfunctions. Present study investigated the reno-protective, altered excret...

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Hlavní autoři: Sheryar Afzal, Munavvar Abdul Sattar, Edward James Johns, Olorunfemi A Eseyin
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2020-01-01
Edice:PLoS ONE
On-line přístup:https://doi.org/10.1371/journal.pone.0229803
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